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Select item 95407221.

Sesquiterpenoid lactones as potential anti-cancer agents: an update on molecular mechanisms and recent studies

Praveen Dhyani, Priyanka Sati, Eshita Sharma, Dharam Chand Attri, Amit Bahukhandi, Bekzat Tynybekov, Agnieszka Szopa, Javad Sharifi-Rad, Daniela Calina, Hafiz A. R. Suleria, William C. Cho

Cancer Cell Int. 2022; 22: 305. Published online 2022 Oct 7. doi: 10.1186/s12935-022-02721-9

PMCID:: PMC9540722

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Select item 75679712.

Fungal Planet description sheets: 1042–1111

P.W. Crous, M.J. Wingfield, Y.-H. Chooi, C.L.M. Gilchrist, E. Lacey, J.I. Pitt, F. Roets, W.J. Swart, J.F. Cano-Lira, N. Valenzuela-Lopez, V. Hubka, R.G. Shivas, A.M. Stchigel, D.G. Holdom, Ž. Jurjević, A.V. Kachalkin, T. Lebel, C. Lock, M.P. Martín, Y.P. Tan, M.A. Tomashevskaya, J.S. Vitelli, I.G. Baseia, V.K. Bhatt, T.E. Brandrud, J.T. De Souza, B. Dima, H.J. Lacey, L. Lombard, P.R. Johnston, A. Morte, V. Papp, A. Rodríguez, E. Rodríguez-Andrade, K.C. Semwal, L. Tegart, Z.G. Abad, A. Akulov, P. Alvarado, A. Alves, J.P. Andrade, F. Arenas, C. Asenjo, J. Ballarà, M.D. Barrett, L.M. Berná, A. Berraf-Tebbal, M.V. Bianchinotti, K. Bransgrove, T.I. Burgess, F.S. Carmo, R. Chávez, A. Čmoková, J.D.W. Dearnaley, A.L.C.M. de A. Santiago, J.F. Freitas-Neto, S. Denman, B. Douglas, F. Dovana, A. Eichmeier, F. Esteve-Raventós, A. Farid, A.G. Fedosova, G. Ferisin, R.J. Ferreira, A. Ferrer, C.N. Figueiredo, Y.F. Figueiredo, C.G. Reinoso-Fuentealba, I. Garrido-Benavent, C.F. Cañete-Gibas, C. Gil-Durán, A.M. Glushakova, M.F.M. Gonçalves, M. González, M. Gorczak, C. Gorton, F.E. Guard, A.L. Guarnizo, J. Guarro, M. Gutiérrez, P. Hamal, L.T. Hien, A.D. Hocking, J. Houbraken, G.C. Hunter, C.A. Inácio, M. Jourdan, V.I. Kapitonov, L. Kelly, T.N. Khanh, K. Kisło, L. Kiss, A. Kiyashko, M. Kolařík, J. Kruse, A. Kubátová, V. Kučera, I. Kučerová, I. Kušan, H.B. Lee, G. Levicán, A. Lewis, N.V. Liem, K. Liimatainen, H.J. Lim, M.N. Lyons, J.G. Maciá-Vicente, V. Magaña-Dueñas, R. Mahiques, E.F. Malysheva, P.A.S. Marbach, P. Marinho, N. Matočec, A.R. McTaggart, A. Mešić, L. Morin, J.M. Muñoz-Mohedano, A. Navarro-Ródenas, C.P. Nicolli, R.L. Oliveira, E. Otsing, C.L. Ovrebo, T.A. Pankratov, A. Paños, A. Paz-Conde, A. Pérez-Sierra, C. Phosri, Á. Pintos, A. Pošta, S. Prencipe, E. Rubio, A. Saitta, L.S. Sales, L. Sanhueza, L.A. Shuttleworth, J. Smith, M.E. Smith, D. Spadaro, M. Spetik, M. Sochor, Z. Sochorová, J.O. Sousa, N. Suwannasai, L. Tedersoo, H.M. Thanh, L.D. Thao, Z. Tkalčec, N. Vaghefi, A.S. Venzhik, A. Verbeken, A. Vizzini, S. Voyron, M. Wainhouse, A.J.S. Whalley, M. Wrzosek, M. Zapata, I. Zeil-Rolfe, J.Z. Groenewald

Persoonia. 2020 Jun; 44: 301–459. Published online 2020 Jun 29. doi: 10.3767/persoonia.2020.44.11

PMCID:: PMC7567971

Article PDF–53M

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PMC Images search for tubuli lactiferus

Figure 4. The diameter of the seminiferous tubuli and the incidence of tubuli with mature sperms. The diameter of 30 seminiferous tubuli per bird was measured and expressed as mean ± standard error (A). The percentage of tubuli, including the mature sperm of 30 tubuli per bird, was calculated and expressed as mean ± standard error (B). Both the diameter of seminiferous tubuli and the incidence of tubuli having mature sperms were significantly lower in BPA-exposed birds.

Effects of bisphenol-A on the growth of comb and testes of male chicken

Can J Vet Res. 2003 Jan;67(1):68-71.
Figure 2.

Immunohistochemistry for PDGF-B in rat kidney. In the control kidney (A; ×50), immunoreactive products were recognized in the convoluted proximal tubuli and distal tubuli. However, the S3 segment of the proximal tubuli was completely negative for PDGF-B. In kidneys at 6 hours after ischemia/reperfusion (B; ×100), some cells of the S3 segment were positive for PDGF-B. The TAL adjacent to the injured tubuli showed strong immunoreactivities. In kidneys at 48 hours (C; ×100), injured proximal tubuli were positive. MR, Medullary ray; S3, the S3 segment of the proximal tubuli; TAL, the thick ascending limb.

Role of PDGF B-Chain and PDGF Receptors in Rat Tubular Regeneration after Acute Injury

Am J Pathol. 1999 Nov;155(5):1689-1699.
Figure 2

RAB38 and HS6ST1 expression across kidney tissues. A: Comparison of RAB38 and HS6ST1 expression (microarray) in tubuli and glomeruli of patients with DKD and control subjects shows significantly higher RAB38 expression in tubuli of DKD patients than in tubuli of control subjects (significance threshold 0.05/6 = 8.3 × 10⁻³ for investigating RAB38, CTSC, and HS6ST1 in tubuli and glomeruli). CTSC expression was not significantly different between DKD case subjects and control subjects in tubuli (P = 0.11) or glomeruli (P = 0.03). Expression levels are shown as robust multiarray average–processed gene intensity values. B: RAB38 and HS6ST1 transcript abundance quantified from RNA sequencing (RNAseq) is detected at high levels in human tubuli but also in glomerular cells. Transcripts were quantified by reads per kilobase of transcript per million mapped (RPKM). The error bars in A and B correspond to the SEM.

Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes

Diabetes. 2016 Mar;65(3):803-817.
Figure 2.

Crocin reduced renal lesions in mice. HE staining of kidney tissue sections. In control group (I), we observed normal appearance of glomeruli and tubuli in the kidney sections. In CDDP treatment group (10 mg/kg) (II), we observed severe degeneration in glomeruli and tubuli as indicated by red arrows. In crocin (6.25 mg/kg body weight) +CDDP treatment group (III), we observed much less degeneration in glomeruli and tubuli as indicated by red arrow. In crocin (12.5 mg/kg body weight) +CDDP treatment group (IV), we observed almost normal appearance of glomeruli and tubuli as indicated by red arrow. In silymarin (100 mg/kg) + CDDP treatment group (V), we observed almost normal appearance of glomeruli and tubuli as indicated by red arrow. Silymarin as antioxidant agent was used as positive control. Scale bar: 50 μm.

Chemotherapy-induced nephrotoxicity was improved by crocin in mouse model

Eur J Histochem. 2022 Sep 20;66(4):3541.